Tellurate enters Escherichia coli K-12 cells via the SulT-type sulfate transporter CysPUWA


Journal article


Jennifer L Goff, N. Yee
FEMS microbiology letters, 2017

Semantic Scholar DOI PubMed
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APA   Click to copy
Goff, J. L., & Yee, N. (2017). Tellurate enters Escherichia coli K-12 cells via the SulT-type sulfate transporter CysPUWA. FEMS Microbiology Letters.


Chicago/Turabian   Click to copy
Goff, Jennifer L, and N. Yee. “Tellurate Enters Escherichia Coli K-12 Cells via the SulT-Type Sulfate Transporter CysPUWA.” FEMS microbiology letters (2017).


MLA   Click to copy
Goff, Jennifer L., and N. Yee. “Tellurate Enters Escherichia Coli K-12 Cells via the SulT-Type Sulfate Transporter CysPUWA.” FEMS Microbiology Letters, 2017.


BibTeX   Click to copy

@article{jennifer2017a,
  title = {Tellurate enters Escherichia coli K-12 cells via the SulT-type sulfate transporter CysPUWA},
  year = {2017},
  journal = {FEMS microbiology letters},
  author = {Goff, Jennifer L and Yee, N.}
}

Abstract

Soluble forms of tellurium are environmental contaminants that are toxic to microorganisms. While tellurite [Te(IV)] is a well-characterized antimicrobial agent, little is known about the interactions of tellurate [Te(VI)] with bacterial cells. In this study, we investigated the role of sulfate transporters in the uptake of tellurate in Escherichia coli K-12. Mutant strains carrying a deletion of the cysW gene in the CysPUWA sulfate transporter system accumulated less cellular tellurium and exhibited higher resistance to tellurate compared with the wild-type strain. Complementation of the mutation restored tellurate sensitivity and uptake. These results indicate that tellurate enters E. coli cells to cause toxic effects via the CysPUWA sulfate transporter.


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